Imdatifan

CAT: 0804-HY-148264Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-148264Size:1 Each

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Description

Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].

CAS Number

2511247-29-1

Product Name Alternative

HIF-2α-IN-7

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/imdatifan.html

Solubility

10 mM in DMSO

Smiles

O[C@]12C3=C(C(F)(C1(F)F)F)C=CC(OC4=CC(C#N)=CC(F)=C4)=C3[C@H](C2)F

Molecular Formula

C18H9F6NO2

Molecular Weight

385.26

References & Citations

[1]Jiping Fu, et al. Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2 (alpha) inhibitors. Patent. WO2020214853A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Imdatifan

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