Benz-AP
CAT:
804-HY-147915
Size:
Inquire
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Benz-AP
- CAS Number: 2416220-53-4
- UNSPSC Description: Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].
- Target Antigen: Carboxylesterase; Reactive Oxygen Species
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/benz-ap.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=C2C=CC=C3C(C=CC(C=C1)=C32)=O)C4=CC=CC=C4
- Molecular Weight: 299.32
- References & Citations: [1]Kailass K, et al. Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence. J Med Chem. 2022 Jun 14.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported