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WNY1613

CAT: 0804-HY-147792Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147792Size:1 Each
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Description
WNY1613 is a potent and selective PI3Kδ inhibitor with piperazinone-containing purine scaffold. WNY1613 induces cancer cell apoptosis and inhibits the phosphorylation of PI3K downstream components in NHL cell lines. WNY1613 exhibits anti-NHL activity in vitro and in vivo[1].
CAS Number
2650546-39-5
UNSPSC
12352005
Target
Apoptosis; PI3K
Type
Reference compound
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wny1613.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC2=NC3=C(N4CCOCC4)N=C(N5C6=CC=CC=C6N=C5CC)N=C3N2C)CCN(C(C7CCC7)=O)C1
Molecular Formula
C29H35N9O3
Molecular Weight
557.65
References & Citations
[1]Zuo WQ, et al. Identification of a potent and selective phosphatidylinositol 3-kinase δ inhibitor for the treatment of non-Hodgkin's lymphoma. Bioorg Chem. 2020;105:104344.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T63942-01WNY1613

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