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FPDT

CAT: 0804-HY-147789Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147789Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FPDT is an anti-glioblastoma agent. FPDT displays the IC50 value of 45–68 μM for GBM cells and >100 μM for astrocytes. Anti-glioblastoma activity of FPDT is linked to downregulation of the AKT pathway[1].
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fpdt.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(O)=C1)C2=CC=C(S2)NC3=CC=C(C=C3)F
Molecular Formula
C16H12FNO2S
Molecular Weight
301.34
References & Citations
[1]Szeliga M, et al. Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway. Bioorg Chem. 2020;105:104362.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5803402FPDT

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