Products for Research Use Only

NAAA-IN-3

CAT: 0804-HY-147775-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-147775-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) . NAAA-IN-3 has the potential for the research of inflammation and pain[1].
CAS Number
1831115-59-3
UNSPSC
12352005
Target
Ceramidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/naaa-in-3.html
Purity
98.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CN1CC(C1)OCC2=CC=C(C=C2)C3=CC=CC=C3
Molecular Formula
C17H16N2O
Molecular Weight
264.32
References & Citations
[1]Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28 (1) :115195.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported