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C5aR-IN-2

CAT: 0804-HY-147586Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147586Size:1 Each
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Description
C5aR-IN-2 is a potent inhibitor of C5aR. Increased level of C5a has been associated with disorders such as autoimmune disorders and inflammatory disorders. C5aR-IN-2 has the potential for the research of inflammation diseases (extracted from patent WO2022028586A1, compound 49) [1].
CAS Number
2761048-06-8
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c5ar-in-2.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(F)=CC=C1)C(N2[C@H]([C@H](C[C@H]3CCC[C@H]32)C(NC4=CC5=C(N(N=C5)C)C=C4)=O)C6=CC=C(C=C6)NC7CCCC7)=O
Molecular Formula
C36H40FN5O2
Molecular Weight
593.73
References & Citations
[1]Gonghua Pan, et al. Compounds as c5ar inhibitors. Patent WO2022028586A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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