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Adipiplon

CAT: 0804-HY-14758Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14758Size:1 Each
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Description
Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the research of a variety of central nervous system (CNS) disorders.
CAS Number
840486-93-3
Product Name Alternative
NG2-73
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/adipiplon.html
Solubility
10 mM in DMSO
Smiles
CCCC1=C(CN2C=CN=C2C3=NC=CC=C3F)N=CN4C1=NC(C)=N4
Molecular Formula
C18H18FN7
Molecular Weight
351.38
References & Citations
[1]Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668 (1-2) :190-193. |[2]Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
T29662-01Adipiplon

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