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Ultevursen

CAT: 0804-HY-147412Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147412Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ultevursen (QR-421a) is a single-stranded RNA based oligonucleotide that is designed to skip exon 13 in the RNA with the aim to stop vision loss in people that have retinitis pigmentosa due to a mutation in exon 13 of the USH2A gene (encoding usherin) . Ultevursen sequence: (P-thio) [2′-O- (2-methoxyethyl) ] (A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C) [1].
CAS Number
2642382-41-8
Product Name Alternative
QR-421a
UNSPSC
12352208
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ultevursen.html
Solubility
10 mM in DMSO
Smiles
[Ultevursen]
Molecular Formula
C273H391N81O144P20S20
Molecular Weight
8372.24
References & Citations
[1]International Nonproprietary Names for Pharmaceutical Substances (INN) . WHO Drug Information, Vol. 36, No. 2, 2022.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3

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