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Arbaclofen placarbil

CAT: 0804-HY-14735Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14735Size:1 Each
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Description
Arbaclofen placarbil is a novel transported proagent of the active R-isomer of baclofen. Baclofen is a racemic GABAB receptor agonist
CAS Number
847353-30-4
Product Name Alternative
XP 19986
UNSPSC
12352005
Hazard Statement
H302
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/arbaclofen-placarbil.html
Solubility
10 mM in DMSO
Smiles
CC(C)C(O[C@H](C(C)C)OC(NC[C@@H](C1=CC=C(C=C1)Cl)CC(O)=O)=O)=O
Molecular Formula
C19H26ClNO6
Molecular Weight
399.87
Precautions
P264-P270-P330-P501
References & Citations
[1]Lal R, Sukbuntherng J, Tai EH, et al. Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen. J Pharmacol Exp Ther. 2009;330 (3) :911-921.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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