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Cavutilide

CAT: 0804-HY-147256-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147256-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cavutilide (Niferidil (free base) ) is a class III antiarrhythmic agent that inhibits hERG K+ channel. Cavutilide has the potential for the study of persistent atrial fibrillation[1][2].
CAS Number
1276186-19-6
Product Name Alternative
Niferidil (free base)
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cavutilide.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C1=CC=C(F)C=C1)CC2CCN(CC)CC2)C3=CC=C([N+]([O-])=O)C=C3
Molecular Formula
C22H26FN3O3
Molecular Weight
399.46
References & Citations
[1]WHO Drug Information, Vol. 36, No. 2, 2022.|[2]Abramochkin DV, et al. Characterization of hERG K+ channel inhibition by the new class III antiarrhythmic drug cavutilide. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jul;397 (7) :5093-5104.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported