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Coronastat

CAT: 0804-HY-147020-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147020-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease. The SARS-CoV-2 3CL protease is a critical agent target for small molecule COVID-19, given its likely agentgability and essentiality in the viral maturation and replication cycle[1].
CAS Number
2922281-15-8
Product Name Alternative
NK01-63
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/coronastat.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
OC(S(=O)(O[Na])=O)[C@H](C[C@@H]1CCNC1=O)NC([C@H](CC(C)C)NC(OCC2=CC(C(F)(F)F)=CC=C2)=O)=O
Molecular Formula
C22H29F3N3NaO8S
Molecular Weight
575.53
References & Citations
[1]Liu H, et al. Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nat Commun. 2022;13 (1) :1891.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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