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ZM514

CAT: 0804-HY-146759Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146759Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZM514 is a potent CD73 inhibitor with IC50s of 1.39 μM and 14.65 μM for hCD73 and mCD73, respectively. ZM514 has low cytotoxicity. ZM514 can be used for researching anticancer[1].
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zm514.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC[C@@]3([C@](CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]43C)C(O)=O)C(C)=C)[H])[H])([C@]1(CC[C@@H](C2(C)C)OC(N6CCCCC6)=O)C)[H])C
Molecular Formula
C36H57NO4
Molecular Weight
567.84
References & Citations
[1]Zhang Y, et al. Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors. Bioorg Med Chem. 2022;59:116672.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T64019-01ZM514

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