VIM-2-IN-1

• UNSPSC Description:

  VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].

• Target Antigen:

  Bacterial; Beta-lactamase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/vim-2-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(OCC1=C(N=NN1)CNS(=O)(C2=CC=C(C=C2)I)=O)=O

• Molecular Weight:

  436.23

• References & Citations:

  [1] Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28(15):115598.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2452118-54-4