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RmlA-IN-2

CAT: 0804-HY-146551Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146551Size:1 Each
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Description
RmlA-IN-2 (Compound 1d) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.303 μM. RmlA-IN-2 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-2 affects bacterial cell wall permeability[1].
CAS Number
2866140-40-9
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rmla-in-2.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=CC=C1)(N(C2=C(NCCCCN)N(CC3=CC=C(Br)C=C3)C(NC2=O)=O)C)=O
Molecular Formula
C22H26BrN5O4S
Molecular Weight
536.44
References & Citations
[1]Xiao G, et al. Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg Med Chem. 2021;50:116477.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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