RmlA-IN-2

• UNSPSC Description:

  RmlA-IN-2 (Compound 1d) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.303 μM. RmlA-IN-2 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-2 affects bacterial cell wall permeability[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/rmla-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=CC=C1)(N(C2=C(NCCCCN)N(CC3=CC=C(Br)C=C3)C(NC2=O)=O)C)=O

• Molecular Weight:

  536.44

• References & Citations:

  [1]Xiao G, et al. Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg Med Chem. 2021;50:116477.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2866140-40-9