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Antifungal agent 30

CAT: 0804-HY-146464Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146464Size:1 Each
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Description
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].
CAS Number
2422019-91-6
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-30.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(F)=C(C=C1)C([Se]CC2=C(C=C(C=C2)Cl)Cl)CN3C=CN=C3
Molecular Formula
C18H14Cl2F2N2Se
Molecular Weight
446.18
References & Citations
[1]Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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