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UniPR505

CAT: 0804-HY-146375-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-146375-01Size:1 mg
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Description
UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties[1].
CAS Number
2938227-14-4
UNSPSC
12352005
Target
Ephrin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unipr505.html
Purity
99.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@@H]([C@]4(CC[C@]3([H])[C@]1(CC[C@H](C2)OC(NCC)=O)C)C)[C@@H](CCC(N[C@@H](CC5=CNC6=C5C=CC=C6)CC(O)=O)=O)C
Molecular Formula
C39H57N3O5
Molecular Weight
647.89
References & Citations
[1]Incerti M, et al. Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties. Eur J Med Chem. 2020 Mar 1;189:112083.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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