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RPR103611

CAT: 0804-HY-146338Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146338Size:1 Each
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Description
RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively[1].
CAS Number
150840-75-8
UNSPSC
12352211
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rpr103611.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC[C@@]3([C@](CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]43C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C(C)=C)[H])[H])([C@]1(CC[C@@H](C2(C)C)O)C)[H])C
Molecular Formula
C46H78N2O6
Molecular Weight
755.12
References & Citations
[1]Reon Takeuchi, et al. Design, synthesis, and bio-evaluation of novel triterpenoid derivatives as anti-HIV-1 compounds. Bioorg Med Chem Lett. 2022 Aug 1;69:128768.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

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CatalogName
GTR19221172-01RPR103611

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