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P1788

CAT: 0804-HY-146317Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146317Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor. P1788 induces DNA damage[1].
CAS Number
2554623-76-4
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p1788.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2(C3=C1C(N(C=C3)C4CC4)=O)CCCCC2
Molecular Formula
C15H17NO3
Molecular Weight
259.30
References & Citations
[1]Hayek S, et al. Cerpegin-derived furo[3,4-c]pyridine-3,4 (1H,5H) -diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition. Eur J Med Chem. 2020 Jan 15;186:111855.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T60409-01P1788