Products for Research Use Only

Antimicrobial agent-1

CAT: 0804-HY-146078Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146078Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines[1].
CAS Number
2579696-45-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimicrobial-agent-1.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O
Molecular Formula
C22H21N3O2S
Molecular Weight
391.49
References & Citations
[1]Dokla EME, et al. Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. Eur J Med Chem. 2020;186:111850.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported