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Antiparasitic agent-4

CAT: 0804-HY-146042Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146042Size:1 Each
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Description
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM) [1].
CAS Number
2253996-66-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-4.html
Solubility
10 mM in DMSO
Smiles
OC(C(C1=NC(C2=CC=CC=C2)=NO1)=C)C3=CC=CN=C3
Molecular Formula
C16H13N3O2
Molecular Weight
279.29
References & Citations
[1]Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania; Trypanosoma

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