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Alicaforsen

CAT: 0804-HY-145728Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145728Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
CAS Number
185229-68-9
Product Name Alternative
ISIS-2302
UNSPSC
12352208
Target
Integrin
Type
Oligonucleotides
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alicaforsen.html
Solubility
10 mM in H2O
Smiles
[Alicaforsen]
Molecular Formula
C192H244N75O98P19S19
Molecular Weight
6370.15
References & Citations
[1]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice. Antisense Nucleic Acid Drug Dev. 1997;7 (5) :473-481. |[2]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys. Toxicology. 1997;120 (2) :145-155.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3

Alternative Products

CatalogName
T64233-01Alicaforsen

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