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UCSF686

CAT: 0804-HY-145699Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145699Size:1 Each
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Description
UCSF686 is a probe with which to study the function of the 5-HT5AR. UCSF686 loses affinity at 5-HT5AR (>10 000 nM) but not at 5-HT1AR, 5-HT2BR, and 5-HT7R. UCSF686 controls for off-target effects[1].
CAS Number
2248852-19-7
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ucsf686.html
Solubility
10 mM in DMSO
Smiles
O=S(N(C)C)(CCNCC1=CC=CC2=NC=CC=C21)=O
Molecular Formula
C14H19N3O2S
Molecular Weight
293.38
References & Citations
[1]Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022;65 (5) :4201-4217.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT5 Receptor;5-HT7 Receptor

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