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HP1142

CAT: 0804-HY-145691Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145691Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HP1142 is a potent and selective inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation) . HP1142 is a benzoimidazole scaffold-based compound. HP1142 has the potential for the research of FLT3/ITD leukemia[1].
CAS Number
381173-58-6
UNSPSC
12352005
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hp1142.html
Solubility
10 mM in DMSO
Smiles
COC(C(OC)=C1)=CC=C1CNC2=CC3=C(C=C2)N(C4=CC=CC=C4)C=N3
Molecular Formula
C22H21N3O2
Molecular Weight
359.42
References & Citations
[1]Tian T, et al. Identification of the Benzoimidazole Compound as a Selective FLT3 Inhibitor by Cell-Based High-Throughput Screening of a Diversity Library. J Med Chem. 2022 Feb 24;65 (4) :3597-3605.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T61329-01HP1142

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