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Itruvone

CAT: 0804-HY-145575Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145575Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Itruvone is a intermediate of 17α-ethinylestradiol (EE2) during Fenton oxidation. Itruvone has an antidepressant effect[1][2]. Itruvone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
21321-89-1
Product Name Alternative
PH10
UNSPSC
12352211
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/itruvone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C#C)C
Molecular Formula
C21H28O
Molecular Weight
296.45
References & Citations
[1]Louis Monti. Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders. Patent WO2014105620 A1.|[2]Li Y, et al. Removal of steroid estrogens from waste activated sludge using Fenton oxidation: influencing factors and degradation intermediates. Chemosphere. 2014 Jun;105:24-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2