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K027

CAT: 0804-HY-144762Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144762Size:1 Each
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Description
K027 is a potent reactivator of Organophosphates (OP) -inhibited acetylcholinesterase (AChE) . K027 can be used for the research of Alzheimer's disease[1].
CAS Number
6586-37-4
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/k027.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1)N.[Br-].[Br-]
Molecular Formula
C15H18Br2N4O2
Molecular Weight
446.14
References & Citations
[1]Zuzana Kohoutova, et al. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :760-767.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE

Alternative Products

CatalogName
GTR19185961-01K027

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