VEGFR-2-IN-13
CAT:
804-HY-144754
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
VEGFR-2-IN-13
- CAS Number: 2839104-01-5
- UNSPSC Description: VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor with an IC50 of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and induces apoptosis[1].
- Target Antigen: Apoptosis; VEGFR
- Type: Reference compound
- Related Pathways: Apoptosis;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/vegfr-2-in-13.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=CC=C(C=C1)C(NC2=CC=CC=C2)=O)CSC3=NC4=C(N5C=NN=C35)C=CC=C4
- Molecular Weight: 454.50
- References & Citations: [1]Alsaif NA, et al. Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies. Bioorg Med Chem. 2021 Sep 15;46:116384.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported