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CO delivery molecule 1

CAT: 0804-HY-144368Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144368Size:1 Each
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Description
CO delivery molecule 1 (compound 4) localizes to the endoplasmic reticulum, mitochondria, and lysosomes. Subcellular localization of CO delivery molecule 1 results in CO-induced toxicity effects. Anti-inflammatory effects of CO delivery molecule 1, as measured by TNF-α suppression, occur at the nanomolar level in the absence of CO release, and are enhanced with visible-light-induced CO release[1].
CAS Number
1972616-04-8
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/co-delivery-molecule-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC3=CC=CC=C3C=C2OC(C4=CC=C(N(CC)CC)C=C4)=C1O
Molecular Formula
C23H21NO3
Molecular Weight
359.42
References & Citations
[1]Lazarus LS, et al. Flavonol-Based Carbon Monoxide Delivery Molecule with Endoplasmic Reticulum, Mitochondria, And Lysosome Localization. ACS Med Chem Lett. 2022;13 (2) :236-242. Published 2022 Feb 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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