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Aβ-IN-2

CAT: 0804-HY-144327Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144327Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aβ-IN-2 is a Aβ1-42 aggregation inhibitor. Aβ-IN-2 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-2 can be used for the research of conformational disorders[1].
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ-in-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]1(CCC2C3C=C(C4=CC5=NC6=C(C(C)=C5C[C@@]4(C3CC[C@@]21C)C)C=CC=C6)OCC)[C@@H](CCCC(C)C)C
Molecular Formula
C37H51NO
Molecular Weight
525.81
References & Citations
[1]Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13 (3) :443-448.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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