LY3154885

CAT: 0804-HY-144291Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144291Size:1 Each
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Description
LY3154885 is an orally active dopamine D1 receptor positive allosteric modulator (PAM) . LY3154885 has an improved agent-agent interactions (DDI) risk profile[1].
CAS Number
[2379422-72-5]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly3154885.html
Solubility
10 mM in DMSO
Smiles
CN1N=CC(C2=CC=CC3=C2C[C@H](CO)N(C(CC4=C(Cl)C=CC=C4Cl)=O)[C@H]3C)=C1
Molecular Formula
C23H23Cl2N3O2
Molecular Weight
444.35
References & Citations
[1]Junliang Hao, et al. Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile. J Med Chem. 2022 Mar 10;65 (5) :3786-3797.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
MF-0046898-01LY3154885

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