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VU0155041 (sodium)

CAT: 0804-HY-14417BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14417BSize:1 Each
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Description
VU0155041 sodium is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD) [1].
CAS Number
1259372-69-4
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0155041-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H](CCCC1)[C@H]1C(O[Na])=O)NC2=CC(Cl)=CC(Cl)=C2
Molecular Formula
C14H14Cl2NNaO3
Molecular Weight
338.16
References & Citations
[1]Niswender CM, et, al. Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov; 74 (5) : 1345-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR4

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A22674-1VU0155041 1mg
A22674-2VU0155041 2mg
A22674-200VU0155041 200mg
A22674-50VU0155041 50mg
A22674-25VU0155041 25mg
A22674-10VU0155041 10mg

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