5-C-heptyl-DNJ

5-C-heptyl-DNJ

• CAS Number: 2734265-63-3
• UNSPSC Description: 5-heptyl-DNJ is a potent GAA agonist with a Ki of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects[1].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-c-heptyl-dnj.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCCCC[C@]1([C@H]([C@@H]([C@H](CN1)O)O)O)CO
• Molecular Weight: 261.36
• References & Citations: [1]Atsushi Kato, et al. 5- C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease. J Med Chem. 2022 Feb 10;65(3):2329-2341.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported