Products for Research Use Only
RegisterLogin

Cas9-IN-2

CAT: 0804-HY-144119Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-144119Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1].
CAS Number
1030133-34-6
UNSPSC
12352005
Target
Bacterial; CRISPR/Cas9
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cas9-in-2.html
Solubility
10 mM in DMSO
Smiles
O=S(NC1=NOC(C)=C1)(C2=C(C)N(C(C3=NC(C)=C(C(N4CCC(CC4)C)=O)S3)=C2)C)=O
Molecular Formula
C21H27N5O4S2
Molecular Weight
477.60
References & Citations
[1]Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65 (4) :3266-3305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-144118-01Cas9-IN-1
HY-E70218Cas9 Nuclease
HY-145692-01Cas9-IN-3
HY-174794Cas9-T2A-GFP mRNA
HY-P77727-01Cas9, S. pyogenes (His)
HY-P701235-01Cas9, S. pyogenes (NLS)
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-P703496Cas9, Streptococcus pyogenes serotype M1
HY-P81938-01Cas9 SA Antibody (YA1683, Rabbit)

Alternative Products

CatalogName
T63126-01Cas9-IN-2
RG-107Saos-2-Cas9 Cell Line
RG-017Caco-2-Cas9 Cell Line
sc-421901Nkx-2.2 CRISPR/Cas9 KO Plasmid (m)
sc-401844Nkx-2.2 CRISPR/Cas9 KO Plasmid (h)
T3265Cas9 Expressing RL95-2 Cell line
RG-086H9c2 (2-1) -Cas9 Cell Line
RG-005MDCK (NBL-2) -Cas9 Cell Line
RG-096U-2 OS-Cas9 Cell Line
T3271Cas9 Expressing HK-2 Cell line

Popular Products