Products for Research Use Only
RegisterLogin

Sebaloxavir marboxil

CAT: 0804-HY-143769Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-143769Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sebaloxavir marboxil (Cap-dependent endonuclease-IN-15) (Compound c-1) is a potent inhibitor of cap-dependent endonuclease (CEN) . Sebaloxavir marboxil inhibits the replication of influenza virus. Sebaloxavir marboxil has the potential for the research of viral infections caused by influenza viruses[1].
CAS Number
2581298-44-2
Product Name Alternative
Cap-dependent endonuclease-IN-15
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cap-dependent-endonuclease-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)OCOC(C(C=C1)=O)=C(N1N([C@@H]2C3=CC=CC=C3[Se]CC4=C(F)C(F)=CC=C24)[C@@]5([H])N6CCOC5)C6=O
Molecular Formula
C27H23F2N3O7Se
Molecular Weight
618.44
References & Citations
[1]Xiaolin Hao, et al. Compounds useful in the treatment of influenza virus infection. Patent CN113226327A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Cap-dependent endonuclease-IN-15
CAS Number2581298-44-2
PubChem CID163196322
IUPAC Name[(3R)-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzoselenepin-11-yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-yl]oxymethyl methyl carbonate
Molecular FormulaC27H23F2N3O7Se
Molecular Weight618.5
Topological Polar Surface Area97.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Heavy Atom Count40
Formal Charge0
Complexity1090
SMILES
COC(=O)OCOC1=C2C(=O)N3CCOC[C@H]3N(N2C=CC1=O)[C@H]4C5=C(C[Se]C6=CC=CC=C46)C(=C(C=C5)F)F
InChI
InChI=1S/C27H23F2N3O7Se/c1-36-27(35)39-14-38-25-19(33)8-9-31-24(25)26(34)30-10-11-37-12-21(30)32(31)23-15-6-7-18(28)22(29)17(15)13-40-20-5-3-2-4-16(20)23/h2-9,21,23H,10-14H2,1H3/t21-,23+/m1/s1
InChIKey
JHFNSOXZQCIAIH-GGAORHGYSA-N
Chemical Structure
2D Structure
2D structure of Cap-dependent endonuclease-IN-15
CAS: 2581298-44-2
CID: 163196322
Formula: C27H23F2N3O7Se
MW: 618.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight618.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Exact Mass619.06693
Monoisotopic Mass619.06693
Topological Polar Surface Area97.9 Ų
Heavy Atom Count40
Formal Charge0
Complexity1090
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-164927-01Tivoxavir marboxil
HY-143744-01Suraxavir marboxil
HY-109025-01Baloxavir marboxil
HY-109025R-01Baloxavir marboxil (Standard)
HY-132894-01Pixavir marboxilo

Alternative Products

CatalogName
B8453-10Baloxavir marboxil
RM-B011511-01Baloxavir Marboxil Impurity 11 (Baloxavir Marboxil Enantiomer)
A17088-500Baloxavir marboxil 500mg
A17088-100Baloxavir marboxil 100mg
A17088-10Baloxavir marboxil 10mg

Popular Products