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SQDG

CAT: 0804-HY-143692Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-143692Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations[1][2][3].
CAS Number
123036-44-2
UNSPSC
12352200
Target
Apoptosis; HSV; Liposome; MDM-2/p53; Topoisomerase
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sqdg.html
Purity
99.0
Solubility
DMSO : 1 mg/mL (ultrasonic; warming)
Smiles
CC/C=C\C/C=C\C/C=C\CCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCC)=O)CO[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CS(=O)(O)=O)=O
Molecular Formula
C43H76O12S
Molecular Weight
817.12
References & Citations
[1]Jeonghwan Kim, et al. Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery. Cell Mol Bioeng. 2020 May 26;13 (5) :463-474.|[2]Nakajima Y, et al., Thylakoid membrane lipid sulfoquinovosyl-diacylglycerol (SQDG) is required for full functioning of photosystem II in Thermosynechococcus elongatus. J Biol Chem. 2018 Sep 21;293 (38) :14786-14797.|[3]Wang H, et al. Antiviral activity of a sulfoquinovosyldiacylglycerol (SQDG) compound isolated from the green alga Caulerpa racemosa[J]. 2007.|[4]Jain CK, et al., Sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effects in vivo. Sci Rep. 2015 Jul 20;5:12082.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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