Tubulin inhibitor 12

Tubulin inhibitor 12

• CAS Number: 92575-00-3
• UNSPSC Description: Tubulin inhibitor 12 (Hit 9) is a novel tubulin inhibitor (IC50=25.3 μM). Tubulin inhibitor 12 shows anti-tumor activity and anti-proliferative activity[1].
• Target Antigen: Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/tubulin-inhibitor-12.html
• Solubility: 10 mM in DMSO
• Smiles: CN(C(C1=CC(C2=CC=CC=C2)=NC3=CC=CC=C31)=O)CC4=CC=CC=C4
• Molecular Weight: 352.43
• References & Citations: [1]Wei Liu, et al. Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation. Bioorg Chem. 2022 Jan;118:105486.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported