RORγt inverse agonist 28
CAT:
804-HY-142703
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RORγt inverse agonist 28
- CAS Number: 2741870-21-1
- UNSPSC Description: RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) [1].
- Target Antigen: ROR
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/rorγt-inverse-agonist-28.html
- Solubility: 10 mM in DMSO
- Smiles: FC(F)(F)OC1=C(C2=C(C=C(C=C2Cl)NC([C@H](C3=CC=C(C=C3)S(C)(=O)=O)CO)=O)Cl)C=CC=C1
- Molecular Weight: 548.36
- References & Citations: [1]Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported