RORγt inverse agonist 28

• UNSPSC Description:

  RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) [1].

• Target Antigen:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rorγt-inverse-agonist-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(F)(F)OC1=C(C2=C(C=C(C=C2Cl)NC([C@H](C3=CC=C(C=C3)S(C)(=O)=O)CO)=O)Cl)C=CC=C1

• Molecular Weight:

  548.36

• References & Citations:

  [1]Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2741870-21-1