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Acreozast

CAT: 0804-HY-14271Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14271Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].
CAS Number
123548-56-1
Product Name Alternative
TYB-2285
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/acreozast.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C(NC(COC(C)=O)=O)=CC(C#N)=C1)Cl)COC(C)=O
Molecular Formula
C15H14ClN3O6
Molecular Weight
367.74
References & Citations
[1]Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM) . Gen Pharmacol. 1993 Sep;24 (5) :1207-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5776285Acreozast

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