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Crisugabalin

CAT: 0804-HY-142240-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-142240-01Size:5 mg
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Description
Crisugabalin (HSK16149) is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit.
CAS Number
2209104-84-5
Product Name Alternative
HSK16149
UNSPSC
12352211
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/crisugabalin.html
Purity
99.88
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)C[C@@]1(CN)[C@](C2)([H])[C@@]3([H])C[C@]2([H])CC[C@@]13[H]
Molecular Formula
C12H19NO2
Molecular Weight
209.28
References & Citations
[1]Gou X, et al. Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain. J Pharmacol Exp Ther. 2021 Mar;376 (3) :330-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched