Products for Research Use Only
RegisterLogin

Thiol-PEG3-phosphonic acid ethyl ester

CAT: 0804-HY-141319Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-141319Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Thiol-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
CAS Number
1360716-43-3
UNSPSC
12352100
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thiol-peg3-phosphonic-acid-ethyl-ester.html
Solubility
10 mM in DMSO
Smiles
O=P(OCC)(CCOCCOCCOCCS)OCC
Molecular Formula
C12H27O6PS
Molecular Weight
330.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

Chemical Information

Thiol-PEG3-phosphonic acid ethyl ester
CAS Number1360716-43-3
PubChem CID102514766
IUPAC Name2-[2-[2-(2-diethoxyphosphorylethoxy)ethoxy]ethoxy]ethanethiol
Molecular FormulaC12H27O6PS
Molecular Weight330.38
XLogP0.1
Topological Polar Surface Area64.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count15
Heavy Atom Count20
Formal Charge0
Complexity244
SMILES
CCOP(=O)(CCOCCOCCOCCS)OCC
InChI
InChI=1S/C12H27O6PS/c1-3-17-19(13,18-4-2)11-9-15-7-5-14-6-8-16-10-12-20/h20H,3-12H2,1-2H3
InChIKey
KAUGTHLCKCMXDS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Thiol-PEG3-phosphonic acid ethyl ester
CAS: 1360716-43-3
CID: 102514766
Formula: C12H27O6PS
MW: 330.38
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight330.38
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count15
Exact Mass330.12659675
Monoisotopic Mass330.12659675
Topological Polar Surface Area64.2 Ų
Heavy Atom Count20
Formal Charge0
Complexity244
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-141318-01Thiol-PEG3-phosphonic acid
HY-140813Azido-PEG3-phosphonic acid ethyl ester
HY-141317S-acetyl-PEG3-phosphonic acid ethyl ester
HY-141304Boc-PEG4-phosphonic acid ethyl ester
HY-141312M-PEG5-phosphonic acid ethyl ester
HY-141303Carboxy-PEG4-phosphonic acid ethyl ester
HY-141311-01M-PEG4-phosphonic acid ethyl ester
HY-141313M-PEG9-phosphonic acid ethyl ester
HY-130146Propargyl-PEG3-phosphonic acid diethyl ester
HY-141321PEG3-bis (phosphonic acid diethyl ester)

Alternative Products

CatalogName
MBS5771696Thiol-PEG3-phosphonic acid ethyl ester
GTR19226681-01Azido-PEG3-phosphonic acid ethyl ester
BIPG1345-01Bromo-PEG3-phosphonic acid ethyl ester
T18658-01S-acetyl-PEG3-phosphonic acid ethyl ester
T16611-01Propargyl-PEG3-phosphonic acid diethyl ester
MBS5768808Bromo-PEG3-phosphonic acid diethyl ester
MBS5769742PEG3-bis(phosphonic acid diethyl ester)
T16455-01PEG3-bis (phosphonic acid diethyl ester)
BIPG1690-01PEG3-bis (phosphonic acid trimethylsilyl ester)
HXC51242-01M-PEG5-phosphonic acid ethyl ester

Popular Products