Methyltetrazine-PEG8-NHS ester

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804-HY-141270

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CAS Number: 2183440-34-6
UNSPSC Description: Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG8-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/methyltetrazine-peg8-nhs-ester.html
Solubility: 10 mM in DMSO
Smiles: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC2=CC=C(C3=NN=C(C)N=N3)C=C2
Molecular Weight: 709.74
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-141270	Methyltetrazine-PEG8-NHS ester
HY-141273-02	Methyltetrazine-PEG8-PFP ester
HY-141273-01	Methyltetrazine-PEG8-PFP ester
HY-141269-05	Methyltetrazine-PEG5-NHS ester
HY-141269-03	Methyltetrazine-PEG5-NHS ester
HY-151758	Methyltetrazine-PEG12-NHS ester
HY-141272-02	Methyltetrazine-PEG24-NHS ester
HY-141272-01	Methyltetrazine-PEG24-NHS ester
HY-141269-02	Methyltetrazine-PEG5-NHS ester
HY-141269-01	Methyltetrazine-PEG5-NHS ester

Cat	Name
T16062-10mg	Methyltetrazine-PEG8-NHS ester
T16062-50mg	Methyltetrazine-PEG8-NHS ester
573055	Methyltetrazine-PEG8-NHS ester
T16062-5mg	Methyltetrazine-PEG8-NHS ester
T16062-1mg	Methyltetrazine-PEG8-NHS ester
T16062-1g	Methyltetrazine-PEG8-NHS ester
sc-496797	Methyltetrazine-NHS ester
573051	Methyltetrazine-NHS ester
T18357-5mg	Methyltetrazine-PEG8-PFP ester
T18357-1g	Methyltetrazine-PEG8-PFP ester