Propargyl-PEG4-beta-D-glucose

Propargyl-PEG4-beta-D-glucose

• CAS Number: 1397682-63-1
• UNSPSC Description: Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/propargyl-peg4-beta-d-glucose.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]([C@H]([C@H]([C@@H](CO)O1)O)O)[C@@H]1OCCOCCOCCOCCOCC#C
• Molecular Weight: 394.41
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported