Carboxyrhodamine 110-PEG3-Azide

Carboxyrhodamine 110-PEG3-Azide

• CAS Number: 1536327-95-3
• UNSPSC Description: Carboxyrhodamine 110-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Carboxyrhodamine 110-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/carboxyrhodamine-110-peg3-azide.html
• Solubility: 10 mM in DMSO
• Smiles: [O-]C(C1=CC(C(NCCOCCOCCOCCN=[N+]=[N-])=O)=CC=C1C2=C(C=CC(N)=C3)C3=[O+]C4=C2C=CC(N)=C4)=O.[O-]C(C5=CC=C(C(NCCOCCOCCOCCN=[N+]=[N-])=O)C=C5C6=C(C=CC(N)=C7)C7=[O+]C8=C6C=CC(N)=C8)=O
• Molecular Weight: 574.60
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported