Azide-PEG9-amido-C4-Boc

Azide-PEG9-amido-C4-Boc

• UNSPSC Description: Azide-PEG9-amido-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG9-amido-C4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/azide-peg9-amido-c4-boc.html
• Solubility: 10 mM in DMSO
• Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC(OC(C)(C)C)=O)=O
• Molecular Weight: 666.80
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported