Azido-PEG3-Sulfone-PEG4-Boc

CAT:

804-HY-140604

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CAS Number: 2055023-76-0
UNSPSC Description: Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/azido-peg3-sulfone-peg4-boc.html
Solubility: 10 mM in DMSO
Smiles: O=C(OC(C)(C)C)CCOCCOCCOCCOCCS(CCOCCOCCOCCN=[N+]=[N-])(=O)=O
Molecular Weight: 571.68
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-140604	Azido-PEG3-Sulfone-PEG4-Boc
HY-140602	Azido-PEG3-Sulfone-PEG4-acid
HY-140565	N-(Azido-PEG3)-N-Boc-PEG4-Boc
HY-140613	Boc-PEG4-sulfone-PEG4-Boc
HY-140566	N-Azido-PEG4-N-Boc-N-PEG3-Boc
HY-130598	N-(Azido-PEG3)-N-Boc-PEG4-acid
HY-140869	N-(Azido-PEG3)-N-bis(PEG4-Boc)
HY-140609	m-PEG3-Sulfone-PEG3-Boc
HY-140612	Propargyl-PEG4-Sulfone-PEG4-Boc
HY-140777-02	Azido-PEG4-Boc