N-(Azido-PEG4)-N-bis(PEG4-acid)

CAT:

804-HY-140519

Size:

100 mg

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CAS Number: 2093152-80-6
UNSPSC Description: N-(Azido-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG4)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-azido-peg4-n-bis-peg4-acid.html
Purity: 98.0
Solubility: 10 mM in DMSO
Smiles: OC(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(O)=O)=O
Molecular Weight: 758.85
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, protect from light)
Clinical Information: No Development Reported

Cat	Name
HY-140519	N-(Azido-PEG4)-N-bis(PEG4-acid)
HY-140518	N-(Azido-PEG3)-N-bis(PEG4-acid)
HY-140866	N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
HY-140531	N-(Biotin-PEG4)-N-bis(PEG4-acid)
HY-140084	N-(Propargyl-PEG4)-N-bis(PEG4-acid)
HY-140870	N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
HY-140867-01	N-(Azido-PEG2)-N-bis(PEG4-Boc)
HY-140867-02	N-(Azido-PEG2)-N-bis(PEG4-Boc)
HY-140869	N-(Azido-PEG3)-N-bis(PEG4-Boc)
HY-140567	N-(Azido-PEG4)-N-Boc-PEG4-Boc