N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester

N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester

• CAS Number: 2093152-78-2
• UNSPSC Description: N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-propargyl-peg2-n-boc-peg3-t-butyl-ester.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC(C)(C)C)N(CCOCCOCC#C)CCOCCOCCOCCC(OC(C)(C)C)=O
• Molecular Weight: 503.63
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported