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OXS007417

CAT: 0804-HY-139877Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139877Size:1 Each
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Description
OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.
CAS Number
2761147-94-6
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxs007417.html
Solubility
10 mM in DMSO
Smiles
FC(F)OC(C=C1)=CC=C1N2C=NC3=CN=C(C4=C(C)C=C(F)C=C4)C=C32
Molecular Formula
C20H14F3N3O
Molecular Weight
369.34
References & Citations
[1]Josa-Culleré L, et al. A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo. J Med Chem. 2021 Nov 11;64 (21) :15608-15628.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T61456-01OXS007417

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