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142I5

CAT: 0804-HY-139865Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139865Size:1 Each
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Description
142I5 is a potent ML-IAP Lys-covalent inhibitor with an IC50 value of 11 nM.
CAS Number
2865171-75-9
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/142i5.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(OC)C(C(NC[C@H](NC([C@@H](NC)C)=O)C(N2[C@H](C(N[C@@H]3CCC4=C3C=CC=C4)=O)CCC2)=O)=O)=C1)(F)=O
Molecular Formula
C29H36FN5O7S
Molecular Weight
617.69
References & Citations
[1]Udompholkul P, et al. Lysine Covalent Antagonists of Melanoma Inhibitors of Apoptosis Protein. J Med Chem. 2021 Nov 11;64 (21) :16147-16158.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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