Ticarcillin

• Description :

  Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H317-H334

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ticarcillin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC([C@H](C1=CSC=C1)C(N[C@H]2[C@]3([H])N(C2=O)[C@H](C(C)(S3)C)C(O)=O)=O)=O

• Molecular Formula :

  C15H16N2O6S2

• Molecular Weight :

  384.43

• Precautions :

  P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501

• References & Citations :

  [1]Cecile Formosa, et al. Nanoscale effects of antibiotics on P. aeruginosa. Nanomedicine. 2012 Jan;8 (1) :12-6.|[2]G B van der Voet, et al. Comparison of the antibacterial activity of azlocillin and ticarcillin in vitro and in irradiated neutropenic mice. J Antimicrob Chemother. 1985 Nov;16 (5) :605-13.|[3]Oriel Spierer, et al. Comparative activity of antimicrobials against Pseudomonas aeruginosa, Achromobacter xylosoxidans and Stenotrophomonas maltophilia keratitis isolates. Br J Ophthalmol. 2018 May;102 (5) :708-712.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• Citation 01 :

  Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0160322.|Microbiol Spectr. 2023 Feb 14;11 (1) :e0303822.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0069223.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|Molecules. 2025 Mar 9;30 (6) :1224.

• CAS Number :

  [34787-01-4]