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Simpinicline

CAT: 0804-HY-139582-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139582-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Simpinicline (OC-02), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, shows potent antiviral activity against the SARS-CoV-2 variants in cell culture with an IC50 of 0.04 µM[1].
CAS Number
753015-44-0
Product Name Alternative
OC-02
UNSPSC
12352005
Target
NAChR; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/simpinicline.html
Purity
99.45
Solubility
10 mM in DMSO
Smiles
[C@@H]1(CCNC1)/C=C/C2=CN=CN=C2
Molecular Formula
C10H13N3
Molecular Weight
175.23
References & Citations
[1]Quik M, et al. α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats. Neuropharmacology. 2013 Aug;71:191-203.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
MBS5801028Simpinicline
MBS5813722Simpinicline citrate

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